Peptide Database

Peptide NameWAP four-disulfide core domain protein 12 (Elafin-like protein II) (Single WAP motif protein 2) (Whey acidic protein 2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC413H652N110O130S10

DescriptionStandard

        MWPNSILVLMTLLISSTLVTGGGVKGEEKRVCPPDYVRCIRQDDPQCYSDNDCGDQEICCFWQCGFKCVLPVKDNSEEQIPQSKV
    

Molecular Weight9558.90 Da

Isoelectric Point (pI)4.55

Net Charge (pH 7.0)-4.56

Net Charge (pH 7.4) -4.92

Charge Density (pH 7.0) -0.0537

GRAVY Index-0.25

Hydrophobic Moment 0.62

Boman Index-0.00

Instability Index49.63

Aliphatic Index 77.76

Aromaticity 0.0706

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3860.30

LogP -39.13

H-bond Donors 136.0

H-bond Acceptors 136.0

Rotatable Bonds 313.0

Heavy Atoms 663.0

Ring Count 14.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0023338 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Protease inhibitor Serine protease inhibitor Enzyme inhibitory Non-hemolytic

TargetEscherichia coli