MYP_103989
gamma-glutamyl-leucine
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Antimicrobial
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Antifungal
Membrane / Ion-channel modulation
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Calcium channel modulation
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Calcium channel inhibitor
Sensory / Food function
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Taste-active peptide
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Venom / Toxin
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General toxin
▸
Toxic
not Standard
2 amino acids
-
contains X representing unresolved or non-standard residue
XL
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0348123
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Prenylated-Trp
Bio-Activity Profile
Antimicrobial
Anticancer
Cytotoxic
RECORD: Rec_0352343
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Prenylated-Trp
Bio-Activity Profile
Antimicrobial
Anticancer
A2780
92.6 μM
IC50
RECORD: Rec_0381490
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Prenylated-Trp
Bio-Activity Profile
Antimicrobial
Anticancer
Hemolytic
RECORD: Rec_0396800
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 45.5%, E 0.0%, T 18.2%, C 36.4% [Linear]
residue-level stereochemical modification [Mixed]
None
Amidation
Bio-Activity Profile
Toxic
Antimicrobial
Hemolytic
RECORD: Rec_0405086
VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Y1: diphosphorylated
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-negative
Escherichia coli
125±1.29 μg/mL
MIC
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