Peptide Database

Peptide NameHepcidin-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC394H608N108O121S12

DescriptionStandard

        MKTLTVAVAVAVVLAFIWIQESAATFHGAQQPEEAVSNEDPAADPQETPVDSWMMPSNRQKRGMKCKFCCNCCNFNGCGVCCDF
    

Molecular Weight9178.47 Da

Isoelectric Point (pI)4.83

Net Charge (pH 7.0)-3.48

Net Charge (pH 7.4) -3.88

Charge Density (pH 7.0) -0.0414

GRAVY Index-0.02

Hydrophobic Moment 0.43

Boman Index0.08

Instability Index47.82

Aliphatic Index 58.10

Aromaticity 0.0833

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3651.25

LogP -40.13

H-bond Donors 128.0

H-bond Acceptors 131.0

Rotatable Bonds 294.0

Heavy Atoms 635.0

Ring Count 15.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0282417 VERIFIED: YES

Provenance & Taxonomy

OrganismScophthalmus maximus [Animal]

FamilyHepcidin

Tax ID52904

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal