Peptide Database

Peptide NameSP-E

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC132H202N32O31

DescriptionStandard

        DKPKKKPPPPAGPPPPPPPPPGPPPPGP
    

Molecular Weight2733.21 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.0985

GRAVY Index-1.75

Hydrophobic Moment 0.29

Boman Index-0.09

Instability Index104.40

Aliphatic Index 3.57

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 823.39

LogP -5.99

H-bond Donors 15.0

H-bond Acceptors 34.0

Rotatable Bonds 54.0

Heavy Atoms 195.0

Ring Count 19.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0404354 VERIFIED: YES

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyPrAMP

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anticancer

TargetKlebsiella pneumoniae

Activity2.386-3.304 μM

MethodMIC

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