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MYP_103937
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Basic Information
SP-E
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
28 amino acids
C132H202N32O31
Standard
Sequence
DKPKKKPPPPAGPPPPPPPPPGPPPPGP
Physicochemical Analysis
2733.21 Da
10.00
2.76
2.55
0.0985
-1.75
0.29
-0.09
104.40
3.57
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
823.39
-5.99
15.0
34.0
54.0
195.0
19.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0081695 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
PrAMP
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
A. fumigatus UP1
58.68 μM
EC50
PaperStructural and functional studies on a proline-rich peptide isolated from swine saliva endowed with antifungal activity towards Cryptococcus neoformans.
RECORD: Rec_0134704 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
PrAMP
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Pseudomonas aeruginosa ATCC 9027
2.662 μM
MIC
PaperStructural and functional studies on a proline-rich peptide isolated from swine saliva endowed with antifungal activity towards Cryptococcus neoformans.
RECORD: Rec_0134959 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
PrAMP
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
but not Staphylococcus aureus
>100 μM
EC50
PaperStructural and functional studies on a proline-rich peptide isolated from swine saliva endowed with antifungal activity towards Cryptococcus neoformans.
RECORD: Rec_0186783 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
PrAMP
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Cryptococcus neoformans 6995
2.215 μM
EC50
PaperStructural and functional studies on a proline-rich peptide isolated from swine saliva endowed with antifungal activity towards Cryptococcus neoformans.
RECORD: Rec_0219854 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Salmonella typhimurium ATCC 14028
1.447
EC50
PMID30046246 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30046246/
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