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MYP_103871
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Basic Information
Cecropin A (1-7) + Melittine (2-9) [A10K][V14K]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C93H161N23O16
Standard
Sequence
KWKLFKKIGKVLKKL
Physicochemical Analysis
1857.42 Da
10.78
6.75
6.54
0.4502
-0.38
0.88
-0.16
-34.65
123.33
0.1333
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
668.65
0.53
24.0
23.0
70.0
132.0
3.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0076656 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC BAA-41
16 μM
MIC
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0112305 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa PAO1
01-2 μM
MIC
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0126009 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0169241 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
8 % hemolysis at 64 μM
Hemolysis
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0240862 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 6538P
04-8 μM
MIC
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
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