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MYP_103863
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Basic Information
L1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C112H168N34O22S2
Standard
Sequence
PEWFKCRRWQWRMKKLGA
Physicochemical Analysis
2406.88 Da
11.01
4.95
4.87
0.2749
-1.34
0.57
-0.38
56.61
27.22
0.2222
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
935.55
-3.83
37.0
29.0
79.0
170.0
8.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0168823 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Lactoferrin-derived peptide
9913
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HT-29
>404 μM
IC50
PaperEnhanced antitumor activity and selectivity of lactoferrin-derived peptides PMID12366526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12366526/
RECORD: Rec_0180138 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID12366526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12366526/
RECORD: Rec_0339657 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US20070104764A1/en PatentUS 2007/0104764 A1
RECORD: Rec_0365730 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Lactoferrin-derived peptides
9913.0
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Antimicrobial
MT-1 (breast cancer)
>404 μM
IC50
PaperEnhanced antitumor activity and selectivity of lactoferrin-derived peptides | https://pubmed.ncbi.nlm.nih.gov/12366526/ PMID12366526 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12366526/
RECORD: Rec_0384526 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Lactoferricin
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli; Staphylococcus aureus
30 μg/mL
MIC
PaperConstruction and synthesis of lactoferricin derivatives with enhanced antibacterial activity | Rekdal, O. et al. | DOI: 10.1002/(SICI)1099-1387(199901)5:1<32::AID-PSC172>3.0.CO;2-9 Evidence URLhttps://www.uniprot.org/uniprotkb/P24627/entry
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