Peptide Database

Peptide NameMotilin(1–12)ghrelin(12–28)

Function Ontology

Gastrointestinal bioactivity ▸ Gastrointestinal motility

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC159H258N46O41

DescriptionStandard

        FVPIFTYGELQRVQQRKESKKPPAKLQPR
    

Molecular Weight3470.03 Da

Isoelectric Point (pI)10.55

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.55

Charge Density (pH 7.0) 0.1642

GRAVY Index-1.10

Hydrophobic Moment 0.48

Boman Index-0.30

Instability Index58.33

Aliphatic Index 63.79

Aromaticity 0.1034

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1440.39

LogP -12.00

H-bond Donors 48.0

H-bond Acceptors 46.0

Rotatable Bonds 115.0

Heavy Atoms 246.0

Ring Count 7.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0179749 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyMotilin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Gastrointestinal motility

TargetGPR38 agonist activity

Activity0.01-0.011 μM

MethodEC50

Half-LifeIntravenouly injected in Sprague-Dawley rats, in vivo; 534 s