Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length513 amino acids

Chemical FormulaC2609H4074N646O749S19

DescriptionStandard

        MEQVLEMCTKMVQVLWGCFLLWNLYISSAQTIYPGIKARATQRALDYGIQAGMEMIEQMVKKRNIPDLKGSESLEFLKIDYVNYNFKNIKINAFSLPNTSLAFVPGVGIRALINHGTANISTDWEIKSPLFQDTGGADLFLSGVYFTGIVVLAWNDFGHPILKLQNCCARVSHSDVSFSGELSVLYNSFSEPMEKPILKNLNKMLCPIITSEVEALNANLSMLKALRKIDNYTLLDYSLISSPEITENYVDLNLKGVFYPLENLTDTPFSSVPFVLPEHSDSMIYIGISEYFFKSASYAYFTAGAFNVTLTTKEIFNHLIRNSQGLGSMLSQIAELYILSQPFMVKVLATEPPVVNLLPGNFTLDIPASFVIFTQSKNSTAKTIVSMDFVASTNVALAILGQRLICSLSLKSFYLSLPESSRSNTEVLRFENILSSILHFGVLPLANAKLQQGFPLPNPQNISLVNSDIEVLEGFVLISTDLKYKTSLKQQPSFHGWEALNLISGQWRGKPAP
    

Molecular Weight57083.37 Da

Isoelectric Point (pI)5.88

Net Charge (pH 7.0)-4.90

Net Charge (pH 7.4) -5.68

Charge Density (pH 7.0) -0.0096

GRAVY Index0.16

Hydrophobic Moment 0.69

Boman Index0.17

Instability Index39.48

Aliphatic Index 103.76

Aromaticity 0.1053

Extinction Coeff. Reduced 59820.00

Extinction Coeff. Oxidized 60195.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008340 VERIFIED: NO

Provenance & Taxonomy

OrganismBalaenoptera musculus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria