Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length250 amino acids

Chemical FormulaC1252H1980N342O388S6

DescriptionStandard

        DKGNPVPHGWHTPPGRDMVRVRKMEWDSSRKAYTFTTEEDPRITIIWTPDSSDVNVPSNTSNQNPVRIPNPVVVDPLPEDTNIEATTSPTLEEKKFADYILILPVSDIPPIYIYLSKPPVEFLEVELYSDFVRRSRQGKYEADHMPSKAAVKAYLKAHYPEMTPEDIELASQDVAAIVIPKKVHQKISETYGGRNTSAQIELDSKNLRAALDRNLDAIKPALKDQGATENQIESARSKMHKLNSEMGLYK
    

Molecular Weight28223.56 Da

Isoelectric Point (pI)5.75

Net Charge (pH 7.0)-4.67

Net Charge (pH 7.4) -5.27

Charge Density (pH 7.0) -0.0187

GRAVY Index-0.66

Hydrophobic Moment 0.60

Boman Index-0.09

Instability Index58.20

Aliphatic Index 78.40

Aromaticity 0.0680

Extinction Coeff. Reduced 31400.00

Extinction Coeff. Oxidized 31400.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0302829 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia alba [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli