Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC365H572N100O109S8

DescriptionStandard

        MTDFFGNTNLAIPILLYTYMRSEFDTDKICGYGTAHCRRTCKTEEFQIGGCPNVYPCCLKKRTPSLSKSNPANK
    

Molecular Weight8361.57 Da

Isoelectric Point (pI)8.82

Net Charge (pH 7.0)3.53

Net Charge (pH 7.4) 3.15

Charge Density (pH 7.0) 0.0477

GRAVY Index-0.46

Hydrophobic Moment 0.43

Boman Index-0.06

Instability Index43.94

Aliphatic Index 55.41

Aromaticity 0.1081

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3382.09

LogP -37.07

H-bond Donors 123.0

H-bond Acceptors 122.0

Rotatable Bonds 271.0

Heavy Atoms 582.0

Ring Count 14.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0350881 VERIFIED: NO

Provenance & Taxonomy

OrganismAiluropoda melanoleuca [Animal]

FamilyDefensin

Tax ID9646

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal