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MYP_103744
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Basic Information
Acyl-CoA-binding protein
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Standard
86 amino acids
C441H702N116O136S2
Standard
Sequence
SQAEFDKAAEEVKRLKTQPTDEEMLFIYSHFKQATVGDVNTDRPGLLDLKGKAKWDSWNKLKGTSKESAMKTYVEKVDELKKKYGI
Physicochemical Analysis
9869.12 Da
8.78
1.56
1.26
0.0181
-0.93
0.78
-0.19
19.23
64.65
0.0930
15470.00
15470.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
4151.77
-38.42
143.0
141.0
346.0
695.0
13.0
90.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0057698 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
ACBP
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Lys7 Acetylation; Lys7 N6-succinyllysine, alternate; Lys16 N6-succinyllysine; Tyr28 Phosphotyrosine; Lys50 Acetylation; Lys54 Acetylation; Lys54 N6-malonyllysine, alternate (By similarity); Lys54 N6-succinyllysine, alternate; Lys60 N6-succinyllysine; Lys76 Acetylation; Lys76 N6-succinyllysine, alternate
Bio-Activity Profile
Neuropeptide Neuroendocrine peptide
Evidence URLhttps://www.uniprot.org/uniprotkb/ACBP_MOUSE/entry
RECORD: Rec_0227101 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0272717 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Acyl-CoA-binding protein
10090
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
7:N6-acetyllysine; 7:N6-succinyllysine; 16:N6-succinyllysine; 28:Phosphotyrosine; 50:N6-acetyllysine; 54:N6-(2-hydroxyisobutyryl)lysine; 54:N6-acetyllysine; 54:N6-malonyllysine; 54:N6-succinyllysine; 60:N6-succinyllysine; 76:N6-acetylly
Bio-Activity Profile
Neuropeptide Neuromodulator Growth regulation Development regulation Receptor modulation Immunomodulatory ACE inhibitory
GABA receptor
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PMID23576753 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23576753/
RECORD: Rec_0318664 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Acyl-CoA-binding protein
10090
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Acetylation
7:N6-acetyllysine; 7:N6-succinyllysine; 16:N6-succinyllysine; 28:Phosphotyrosine; 50:N6-acetyllysine; 54:N6-(2-hydroxyisobutyryl)lysine; 54:N6-acetyllysine; 54:N6-malonyllysine; 54:N6-succinyllysine; 60:N6-succinyllysine; 76:N6-acetylly
Bio-Activity Profile
Neuropeptide Neuromodulator Growth regulation Development regulation Receptor modulation Immunomodulatory ACE inhibitory
Mammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour
PMID23576753 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23576753/