Peptide Database

Peptide NameCalcitonin receptor-stimulating peptide 2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC206H348N72O67S4

DescriptionStandard

        SCNRATCVTHKMAGSLSRSGSEIKRNFMSTNVGSKAFGQRSRDLQK
    

Molecular Weight5033.67 Da

Isoelectric Point (pI)10.96

Net Charge (pH 7.0)6.53

Net Charge (pH 7.4) 6.23

Charge Density (pH 7.0) 0.1419

GRAVY Index-0.77

Hydrophobic Moment 0.71

Boman Index-0.27

Instability Index80.34

Aliphatic Index 44.57

Aromaticity 0.0435

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2327.66

LogP -35.52

H-bond Donors 87.0

H-bond Acceptors 79.0

Rotatable Bonds 177.0

Heavy Atoms 349.0

Ring Count 3.0

Amide Bonds 50.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0095607 VERIFIED: NO

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyCalcitonin

Tax ID9925

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-7

Bio-Activity Profile

Function

Hormone Calcium-regulatory peptide

RECORD: Rec_0111629 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0291715 VERIFIED: NO

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyCalcitonin receptor-stimulating peptide

Tax ID9925

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-7

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour