Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length407 amino acids

Chemical FormulaC2022H3253N501O582S20

DescriptionStandard

        MFLCLALLTLLPATVSISPGVKVELTQKGIDYGRQLGIASIQSKLKTIRIPDISGTTNVPAVGKVKYSLSGLQLLDVGLPKSALDLVTGSGVRLSIGDAYMKLHLRSVPSAEYELLKFGRKSLEKQICPLVQTAVSELNPELKTMNVLAKVDQYAEIEYSMVSSPVISNTSLVLNLKGEFYNIGKHQEPPFTATDFSMPTEANNMMYMGISAFTVNSAAFVYTTAGILSLYITDDMIPKSSPFRLTTKSFGIFVPQVEEKFPDLPMKLLVKAVKSPTVTFEPDNMTIQAAATVTAYAIQPNATLSPLFVLSLESSVSGRVFVSGIKLAGEVTLQKMNMTLVTSYVGDFRVRTALLHQPQFIKCVFPFTERLAQGYPLPMIGKMKLVSSQLHILKDYMLIGTDVQFMD
    

Molecular Weight44534.76 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)4.85

Net Charge (pH 7.4) 4.28

Charge Density (pH 7.0) 0.0119

GRAVY Index0.23

Hydrophobic Moment 0.66

Boman Index0.17

Instability Index39.04

Aliphatic Index 102.95

Aromaticity 0.0811

Extinction Coeff. Reduced 20860.00

Extinction Coeff. Oxidized 20985.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0057016 VERIFIED: NO

Provenance & Taxonomy

OrganismSalarias fasciatus (Jewelled blenny) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria