MYP_103615
B1-L-3
Anticancer
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Standard
15 amino acids
C91H151N25O18
Standard
VKRFKSFFRSLKKLV
1883.33 Da
12.00
5.73
5.51
0.3820
-0.12
0.88
-0.24
37.10
90.67
0.2000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
739.06
-3.66
28.0
24.0
67.0
134.0
3.0
14.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0017936
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
Amidation
Stapled: Ⓧ are cross-linked by hydrocarbon stapling
Bio-Activity Profile
Anticancer
U87
3.59±1.20 μM
IC50
RECORD: Rec_0034243
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
Amidation
Stapled: Ⓧ are cross-linked by hydrocarbon stapling
Bio-Activity Profile
Hemolytic
human red blood cells
>80 μM
HC50
RECORD: Rec_0275149
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
Amidation
Stapled: Ⓧ are cross-linked by hydrocarbon stapling
Bio-Activity Profile
Anticancer
MCF-7
5.478±0.89 μM
IC50
RECORD: Rec_0330342
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
hydrocarbon-stapled side-chain cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
Amidation
Stapled: Ⓧ are cross-linked by hydrocarbon stapling
Bio-Activity Profile
Anticancer
Huh-7
5.96±0.54 μM
IC50