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MYP_103606
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
20 amino acids
C104H176N34O24
Standard
Sequence
FIGLLISAGKAIHDLIRRRH
Physicochemical Analysis
2286.72 Da
11.71
2.93
2.63
0.1467
0.34
0.83
0.06
78.33
146.50
0.0500
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
942.83
-6.21
35.0
29.0
78.0
162.0
3.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0295469 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0296751 VERIFIED: YES
Provenance & Taxonomy
Pagrus major [Animal]
Pleurocidin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus iniae F-8502
PMID12581207 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12581207/
RECORD: Rec_0320815 VERIFIED: YES
Provenance & Taxonomy
Chrysophrys major [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Aeromonas salmonicida NCMB 1102
10 μM
MIC
PMID12581207 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12581207/
RECORD: Rec_0321074 VERIFIED: YES
Provenance & Taxonomy
Chrysophrys major [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
iniae F-8502
10 μM
MIC
PMID12581207 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12581207/
RECORD: Rec_0327161 VERIFIED: YES
Provenance & Taxonomy
Chrysophrys major [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli WT-2
0.25 μM
MIC
PMID12581207 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12581207/
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