Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length590 amino acids

Chemical FormulaC2782H4409N827O788S13

DescriptionStandard

        MNDSSVGFAEDVGVRLAVRGARIQLSANWSAQLGTFQDSGVVQLHVADLAVAVLLGLSVDEGGRPAVWAAGCDARGTDLHLEFHRGQSWLYNLLVPLFQRTLRQQLNKQLCVELEKSISRMEASLKRMRVSPQLDPFAAIDLSLLGRPDITAEHGDVSLKGEFFGVGRRWQSPFSPKPVGLPEAHEPMVLLALTEFVANSAAFVYFTAGALRRNISGEALPRRFPIQLRTKSLGSFSPQLQELFPDLPMELQLSARRQPLLSCHPDALHGTLYGSAEAFVVLPNTTRAPVFLLDIVSAWPRGAGVLLGSYWGLTGVLLGSYWGPMGAVGTAPVSPTSPLAAGRQRDGEADHQWEQAGGHRAADEPQRGAGDLAGGAAAGEEAGERAEIRAVAFWGALGKQAAPVGGPAAHPPRPQPGSPAPLAARGLHAPRHGPAVRALRPAAAGDPRTPSPSPSLSPFLGGVQQGFNNPPPPCPGTRSSRLARGMEPAATAPAHRHRQREGTGLKTPPKTSPRACRILRGGVPVPVPVPVLVPVLVPVLVLVLVLGPSRVPPPNQRLAQRPGPMSPNGDGHRSEDLGWGRAQEPGPSKK
    

Molecular Weight62465.68 Da

Isoelectric Point (pI)9.91

Net Charge (pH 7.0)13.84

Net Charge (pH 7.4) 12.71

Charge Density (pH 7.0) 0.0235

GRAVY Index-0.19

Hydrophobic Moment 0.74

Boman Index0.05

Instability Index56.16

Aliphatic Index 84.88

Aromaticity 0.0576

Extinction Coeff. Reduced 62450.00

Extinction Coeff. Oxidized 62700.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0424120 VERIFIED: NO

Provenance & Taxonomy

OrganismAnas zonorhyncha [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria