Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length435 amino acids

Chemical FormulaC2143H3401N585O618S16

DescriptionStandard

        AQQQGIAILEKELAQLTLPDISGDSRVLHVGKVRYSFSSCEADSRSLLQALSLTNISFLSPSPCSRGHGSFNLKVENVYMKIILRLGSDTTGKPTISTSDCSARISKVRVRFSGKLGWLYNLFHRVIESKLRKNLERKVCDNVVESVQNELQTYIRTLRVTARIDDKIGIDYSLVAPPRATAQSLDADLKGEFYSLAHRSTVPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYHKAGALVFEITEAMIPKESEFGLDTSAFSAFIPQLEEMYPNMPMKFRLSTPTAPFLTIGPGGISFQPIVDAQAYAILPNSSLAPLFLLSLVRNVSAVINVRSGRIVGSLDVGRIRLSLKDSAVGHFQVRMMQSLTNILTSSILLPRLNGVGRATCPNAFSLQGCDGCWAMQLPGPVAAQHFLSFSQNFLLLGADVRFQPQ
    

Molecular Weight47761.52 Da

Isoelectric Point (pI)9.20

Net Charge (pH 7.0)9.46

Net Charge (pH 7.4) 8.69

Charge Density (pH 7.0) 0.0218

GRAVY Index0.06

Hydrophobic Moment 0.70

Boman Index0.09

Instability Index40.27

Aliphatic Index 96.18

Aromaticity 0.0874

Extinction Coeff. Reduced 27390.00

Extinction Coeff. Oxidized 27765.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0094365 VERIFIED: NO

Provenance & Taxonomy

OrganismVidua macroura [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria