Peptide Database

Peptide NameMelanotropin alpha

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Regulatory peptide ▸ Cell-cell communication

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC83H121N25O21S

DescriptionStandard

        SYSMEHFRWGKPVGR
    

Molecular Weight1837.07 Da

Isoelectric Point (pI)9.98

Net Charge (pH 7.0)1.55

Net Charge (pH 7.4) 1.29

Charge Density (pH 7.0) 0.1032

GRAVY Index-1.13

Hydrophobic Moment 0.68

Boman Index-0.20

Instability Index25.16

Aliphatic Index 19.33

Aromaticity 0.2000

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 754.21

LogP -6.25

H-bond Donors 28.0

H-bond Acceptors 25.0

Rotatable Bonds 57.0

Heavy Atoms 130.0

Ring Count 6.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0165149 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyPOMC

Tax ID7962

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone precursor Neuropeptide precursor

RECORD: Rec_0226657 VERIFIED: YES

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyMelanocyte-stimulating hormone

Tax ID7962

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0315311 VERIFIED: NO

Provenance & Taxonomy

OrganismThunnus obesus [Animal]

FamilyPOMC

Tax ID8241

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone precursor Neuropeptide precursor

RECORD: Rec_0336335 VERIFIED: NO

Provenance & Taxonomy

OrganismThunnus obesus [Animal]

FamilyMelanocyte-stimulating hormone

Tax ID8241

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0352266 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 0.0%, T 60.0%, C 40.0% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-Cell Communication Hormones