Peptide Database

Peptide NameBeta-defensin 125

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length157 amino acids

Chemical FormulaC771H1223N203O244S13

DescriptionStandard

        MNLLMLTFIICGLLTQVTKGSFEPQKCWKNNIGHCRRRCLDTERYILLCRNKLSCCISIIISHEYTRRPAFPVIHLEDITFDYSDVDSFTGSPVSMLNDLITFDTTKFGETITPETNTPETTMPPSETTSSKTTMPPSETATSETMPPPSQTALTHN
    

Molecular Weight17657.02 Da

Isoelectric Point (pI)5.51

Net Charge (pH 7.0)-4.19

Net Charge (pH 7.4) -4.75

Charge Density (pH 7.0) -0.0267

GRAVY Index-0.28

Hydrophobic Moment 0.60

Boman Index0.02

Instability Index69.64

Aliphatic Index 71.40

Aromaticity 0.0701

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7123.24

LogP -79.32

H-bond Donors 253.0

H-bond Acceptors 257.0

Rotatable Bonds 567.0

Heavy Atoms 1231.0

Ring Count 29.0

Amide Bonds 166.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0085139 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo pygmaeus [Animal]

FamilyDefensin

Tax ID9600

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence