Peptide Database

Peptide NameC12-NH- Dermaseptin S4 (1-14)[M4K] -AMD

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC77H135N19O16

DescriptionStandard

        ALWKTLLKKVLKAA
    

Molecular Weight1583.01 Da

Isoelectric Point (pI)10.48

Net Charge (pH 7.0)3.79

Net Charge (pH 7.4) 3.60

Charge Density (pH 7.0) 0.2708

GRAVY Index0.54

Hydrophobic Moment 0.66

Boman Index0.14

Instability Index8.01

Aliphatic Index 153.57

Aromaticity 0.0714

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 581.72

LogP -0.78

H-bond Donors 21.0

H-bond Acceptors 20.0

Rotatable Bonds 55.0

Heavy Atoms 112.0

Ring Count 2.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0225400 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDermaseptin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli O157:H7 ATCC 43895

Activity4 μM

MethodMIC