Peptide Database

Peptide NameBeta-defensin 12 (BD-12) (mBD-12) (Defensin; beta 12)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC400H610N106O107S8

DescriptionStandard

        MALSREVFYFGFALFFIVVELPSGSWAGLEYSQSFPGGEIAVCETCRLGRGKCRRTCIESEKIAGWCKLNFFCCRERI
    

Molecular Weight8872.29 Da

Isoelectric Point (pI)8.21

Net Charge (pH 7.0)1.45

Net Charge (pH 7.4) 1.11

Charge Density (pH 7.0) 0.0186

GRAVY Index0.23

Hydrophobic Moment 0.56

Boman Index0.10

Instability Index46.90

Aliphatic Index 76.28

Aromaticity 0.1538

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3416.26

LogP -27.43

H-bond Donors 130.0

H-bond Acceptors 117.0

Rotatable Bonds 290.0

Heavy Atoms 621.0

Ring Count 16.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0230490 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic