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MYP_103465
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Basic Information
Esculentin-2CHa [D20K,D27K]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
37 amino acids
C177H303N49O43S2
Standard
Sequence
GFSSIFRGVAKFASKGLGKKLAKLGVKLVACKISKQC
Physicochemical Analysis
3869.73 Da
10.49
8.73
8.49
0.2360
0.35
0.75
0.09
14.32
97.57
0.0811
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1504.99
-13.55
56.0
54.0
139.0
271.0
3.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0171851 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human erythrocytes
11 μM
Hemolysis
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0238941 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human lung carcinoma A549
3 μM
LC50
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0256919 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus V4180
3 μM
MIC
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0282138 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii NM8
3 μM
MIC
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0289369 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii NM35
1.5 μM
MIC
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
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