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MYP_103465
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Basic Information
Esculentin-2CHa [D20K,D27K]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
37 amino acids
C177H303N49O43S2
Standard
Sequence
GFSSIFRGVAKFASKGLGKKLAKLGVKLVACKISKQC
Physicochemical Analysis
3869.73 Da
10.49
8.73
8.49
0.2360
0.35
0.75
0.09
14.32
97.57
0.0811
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1504.99
-13.55
56.0
54.0
139.0
271.0
3.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0060948 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
3 μM
MIC
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0084144 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus 127/08
6 μM
MIC
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0118415 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
11 μM
Hemolysis
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0120700 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
RECORD: Rec_0159243 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
A549
3 μM
LC50
PMID23159562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23159562/
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