Peptide Database

Peptide NameT-110

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV

Antiviral ▸ Anti-Pneumovirus ▸ Anti-RSV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Therapeutic / Biomedical activity ▸ Protective bioactivity ▸ Cell protection ▸ Cytoprotection

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC179H280N46O57

DescriptionStandard

        PLVFPSDEFDASISQVNEKINQSLAFIRKSDELLH
    

Molecular Weight3988.41 Da

Isoelectric Point (pI)4.58

Net Charge (pH 7.0)-2.94

Net Charge (pH 7.4) -3.06

Charge Density (pH 7.0) -0.0841

GRAVY Index-0.25

Hydrophobic Moment 0.55

Boman Index0.02

Instability Index35.57

Aliphatic Index 100.29

Aromaticity 0.0857

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1669.87

LogP -16.04

H-bond Donors 56.0

H-bond Acceptors 55.0

Rotatable Bonds 134.0

Heavy Atoms 282.0

Ring Count 6.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0367524 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman orthopneumovirus [Virus]

FamilyVirus-derived peptide

Tax ID11250;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Fusion inhibitor

TargetRespiratory syncytial virus (Fusion); Vero

MethodImmunoprecipitation

PaperMethods for the inhibition of respiratory syncytial virus transmission | Dani Paul Bolognesi, Thomas James Matthews, Carl T. Wild, Shawn O'Lin Barney,Dennis Michael Lambert, Stephen Robert Petteway | Trimeris, Inc., Durham NC | Patent:US6440656 Evidence URLhttps://patents.google.com/patent/US6440656/en PatentUS6440656

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