Peptide Database

Peptide NameGallinacin-1 (Gal-1) (Beta-defensin 1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC328H528N88O80S7

DescriptionStandard

        MRIVYLLLPFILLLAQGAAGSSQALGRKSDCFRKSGFCAFLKCPSLTLISGKCSRFYLCCKRIWG
    

Molecular Weight7208.70 Da

Isoelectric Point (pI)9.81

Net Charge (pH 7.0)8.44

Net Charge (pH 7.4) 8.12

Charge Density (pH 7.0) 0.1298

GRAVY Index0.55

Hydrophobic Moment 0.57

Boman Index0.16

Instability Index34.44

Aliphatic Index 102.15

Aromaticity 0.1231

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2689.31

LogP -20.87

H-bond Donors 104.0

H-bond Acceptors 96.0

Rotatable Bonds 239.0

Heavy Atoms 503.0

Ring Count 11.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0147051 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9031

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0406579 VERIFIED: YES