Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC167H271N51O56S2

DescriptionStandard

        KCNTVTCATQRLANFLVRSSNNFGAILSSTNVGSNTY
    

Molecular Weight3953.38 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.50

Charge Density (pH 7.0) 0.0740

GRAVY Index-0.07

Hydrophobic Moment 0.67

Boman Index0.02

Instability Index11.52

Aliphatic Index 73.78

Aromaticity 0.0811

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1784.90

LogP -27.34

H-bond Donors 65.0

H-bond Acceptors 61.0

Rotatable Bonds 129.0

Heavy Atoms 276.0

Ring Count 3.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0158876 VERIFIED: YES

Provenance & Taxonomy

OrganismGorilla gorilla [Animal]

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)