Peptide Database

Peptide NameCycloviolacin O7

Function Ontology

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Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC124H199N29O41S6

DescriptionStandard

        SIPCGESCVYIPCISSLLGCSCESKVCY
    

Molecular Weight2944.47 Da

Isoelectric Point (pI)4.53

Net Charge (pH 7.0)-1.60

Net Charge (pH 7.4) -1.90

Charge Density (pH 7.0) -0.0570

GRAVY Index0.79

Hydrophobic Moment 0.29

Boman Index0.28

Instability Index35.01

Aliphatic Index 90.36

Aromaticity 0.0714

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1093.90

LogP -12.41

H-bond Donors 44.0

H-bond Acceptors 46.0

Rotatable Bonds 91.0

Heavy Atoms 200.0

Ring Count 4.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0216460 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)