Peptide Database

Peptide NameC-terminal extension peptide

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC315H476N82O107S2

DescriptionStandard

        SIEEYPYAYDEADRSSAAVFSEGDKPSDGYQQWKESLLNLLKMIEVNEYRNSKAMREASVYN
    

Molecular Weight7187.76 Da

Isoelectric Point (pI)4.49

Net Charge (pH 7.0)-5.52

Net Charge (pH 7.4) -5.76

Charge Density (pH 7.0) -0.0891

GRAVY Index-0.92

Hydrophobic Moment 0.54

Boman Index-0.15

Instability Index55.70

Aliphatic Index 61.45

Aromaticity 0.1290

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14440.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3115.77

LogP -32.13

H-bond Donors 107.0

H-bond Acceptors 104.0

Rotatable Bonds 240.0

Heavy Atoms 506.0

Ring Count 11.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0039691 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina orientalis [Animal]

FamilyC-terminal extension peptide

Tax ID8346

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0252093 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0349630 VERIFIED: NO

Provenance & Taxonomy

OrganismBombina orientalis [Animal]

FamilyBombesin/neuromedin-B/ranatensin

Tax ID8346

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Hormone