Peptide Database

Peptide NameInsulin-2 B chain

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC158H235N39O41S3

DescriptionStandard

        FVKQHLCGSHLVEALYLVCGERGFFYTPMS
    

Molecular Weight3432.99 Da

Isoelectric Point (pI)6.90

Net Charge (pH 7.0)-0.08

Net Charge (pH 7.4) -0.42

Charge Density (pH 7.0) -0.0028

GRAVY Index0.40

Hydrophobic Moment 0.33

Boman Index0.25

Instability Index31.41

Aliphatic Index 84.33

Aromaticity 0.1667

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1262.55

LogP -8.05

H-bond Donors 46.0

H-bond Acceptors 46.0

Rotatable Bonds 108.0

Heavy Atoms 241.0

Ring Count 8.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0148585 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyInsulin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0311691 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyInsulin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0312235 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyInsulin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0357432 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyInsulin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic