Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC466H741N135O129S8

DescriptionStandard

        MKFLLLVLAALGFLTQVIPASGGGSKCVSDTPGYCRTHCHRGETALFMCSPFRKCCISYSFLPQPDLPQLVGNHWPSRSRNTQRKNKKQQTTVTP
    

Molecular Weight10555.22 Da

Isoelectric Point (pI)9.75

Net Charge (pH 7.0)8.70

Net Charge (pH 7.4) 8.23

Charge Density (pH 7.0) 0.0916

GRAVY Index-0.26

Hydrophobic Moment 0.44

Boman Index-0.01

Instability Index41.44

Aliphatic Index 68.74

Aromaticity 0.0842

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4221.60

LogP -46.46

H-bond Donors 152.0

H-bond Acceptors 149.0

Rotatable Bonds 339.0

Heavy Atoms 738.0

Ring Count 20.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0278965 VERIFIED: NO

Provenance & Taxonomy

OrganismTheropithecus gelada [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0320458 VERIFIED: NO

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyBeta-defensin; Defensin

Tax ID9555

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic