Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC437H705N129O137S7

DescriptionStandard

        MRTLAILAAILLFTLQAQAESLQERADEVQPGEDDQDLAVSFEENRLSTLRASGSQARRTCYCRTSRCYTPEFHSGKCLFKGLTYKLCCR
    

Molecular Weight10182.51 Da

Isoelectric Point (pI)7.58

Net Charge (pH 7.0)0.55

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0061

GRAVY Index-0.34

Hydrophobic Moment 0.56

Boman Index-0.12

Instability Index44.53

Aliphatic Index 77.11

Aromaticity 0.0778

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4355.32

LogP -48.88

H-bond Donors 161.0

H-bond Acceptors 146.0

Rotatable Bonds 343.0

Heavy Atoms 710.0

Ring Count 10.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0177377 VERIFIED: NO

Provenance & Taxonomy

OrganismMandrillus leucophaeus [Animal]

FamilyDefensin

Tax ID9568

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence