Peptide Database

Peptide NameToxin LyeTx 1 (1-15)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC83H136N20O18

DescriptionStandard

        IWLTALKFLGKNLGK
    

Molecular Weight1702.09 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.1838

GRAVY Index0.45

Hydrophobic Moment 0.55

Boman Index0.26

Instability Index0.58

Aliphatic Index 136.67

Aromaticity 0.1333

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 627.89

LogP -1.69

H-bond Donors 22.0

H-bond Acceptors 21.0

Rotatable Bonds 58.0

Heavy Atoms 121.0

Ring Count 3.0

Amide Bonds 15.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0379978 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetEscherichia coli ATCC 25922

Activity14.93 μM

MethodMBC

RECORD: Rec_0408289 VERIFIED: YES