Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC443H733N131O124S9

DescriptionStandard

        MKLLVLFLAILLAVEEPVVSVECWMDGHCRLLCRDNEDSIIRCRNRKRCCVPSRYLTIEPVTIHGILDWTTPQISTTAPQMKRNKNRG
    

Molecular Weight10166.95 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)3.63

Net Charge (pH 7.4) 3.21

Charge Density (pH 7.0) 0.0412

GRAVY Index-0.08

Hydrophobic Moment 0.59

Boman Index-0.05

Instability Index65.45

Aliphatic Index 101.82

Aromaticity 0.0455

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4117.96

LogP -36.76

H-bond Donors 151.0

H-bond Acceptors 139.0

Rotatable Bonds 337.0

Heavy Atoms 707.0

Ring Count 13.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0024561 VERIFIED: NO

Provenance & Taxonomy

OrganismCebus imitator [Animal]

FamilyDefensin

Tax ID9516

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence