Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length221 amino acids

Chemical FormulaC1104H1690N250O338S8

DescriptionStandard

        IDELVEVDYSLTSLPAVFPSFLDLDLKGIVYPTGNYSGPPYVAAPFTVPDQSNSMLSLAFSEAFFQTSSFAYYTAGAFNITIAEETCSYFNISTEIFSSIIPEVAEYSVTPNPVLLKLMATEMPLISLEQDSFTVLLQGSMEVFAVLPDSSTQSLFTMNIAANTSIAPNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANGKV
    

Molecular Weight24129.22 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-17.14

Net Charge (pH 7.4) -17.47

Charge Density (pH 7.0) -0.0775

GRAVY Index0.40

Hydrophobic Moment 0.53

Boman Index0.27

Instability Index49.20

Aliphatic Index 101.49

Aromaticity 0.1176

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0058282 VERIFIED: NO

Provenance & Taxonomy

OrganismBucco capensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria