Peptide Database

Peptide NameDefensin-C

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC442H711N131O144S9

DescriptionStandard

        MNSLGTVCLAALCLFAIVSTGSGFPQESADQVQSYANTLFDELPEQSYQAAAENLRLKRATCDLLSGLGVNDSACAAHCIARGNRGGYCNSKKVCVCRN
    

Molecular Weight10452.75 Da

Isoelectric Point (pI)6.51

Net Charge (pH 7.0)-0.48

Net Charge (pH 7.4) -0.88

Charge Density (pH 7.0) -0.0049

GRAVY Index0.02

Hydrophobic Moment 0.61

Boman Index0.05

Instability Index43.98

Aliphatic Index 81.92

Aromaticity 0.0606

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4452.94

LogP -57.53

H-bond Donors 161.0

H-bond Acceptors 154.0

Rotatable Bonds 346.0

Heavy Atoms 726.0

Ring Count 9.0

Amide Bonds 110.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0395166 VERIFIED: NO

Provenance & Taxonomy

OrganismCulex pipiens [Animal]

FamilyDefensin

Tax ID7175

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal