Peptide Database

Peptide NameInsulin A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC102H154N30O33S4

DescriptionStandard

        GIVDQCCHRPCDIFDLQNYCN
    

Molecular Weight2456.76 Da

Isoelectric Point (pI)4.41

Net Charge (pH 7.0)-2.19

Net Charge (pH 7.4) -2.51

Charge Density (pH 7.0) -0.1043

GRAVY Index-0.27

Hydrophobic Moment 0.51

Boman Index-0.04

Instability Index42.37

Aliphatic Index 69.52

Aromaticity 0.0952

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1031.60

LogP -11.13

H-bond Donors 37.0

H-bond Acceptors 36.0

Rotatable Bonds 77.0

Heavy Atoms 169.0

Ring Count 4.0

Amide Bonds 24.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0118178 VERIFIED: YES

Provenance & Taxonomy

OrganismGadus morhua callarias [Animal]

FamilyInsulin

Tax ID8053

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour