Peptide Database

Peptide NameTritrpticin [P5A][R2,3,12,13K]

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC94H130N20O14

DescriptionStandard

        VKKFAWWWPFLKK
    

Molecular Weight1764.16 Da

Isoelectric Point (pI)10.48

Net Charge (pH 7.0)3.73

Net Charge (pH 7.4) 3.51

Charge Density (pH 7.0) 0.2869

GRAVY Index-0.35

Hydrophobic Moment 0.36

Boman Index0.13

Instability Index15.30

Aliphatic Index 60.00

Aromaticity 0.3846

Extinction Coeff. Reduced 16500.00

Extinction Coeff. Oxidized 16500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 555.18

LogP 3.62

H-bond Donors 20.0

H-bond Acceptors 18.0

Rotatable Bonds 53.0

Heavy Atoms 128.0

Ring Count 9.0

Amide Bonds 12.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0358423 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman red blood cells

Activity50 μM

MethodHemolysis

FIRST PREV 1 2

Showing 1 records on this page Ã‚Â· Page 2 of 2