Peptide Database

Peptide NameAntileukoproteinase (ALP) (BLPI) (HUSI-1) (Mucus proteinase inhibitor) (MPI) (Protease inhibitor WAP4) (Secretory leukocyte protease inhibitor) (Seminal proteinase inhibitor) (WAP four-disulfide core domain protein 4)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium

Antimicrobial ▸ Antibiotic activity

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Wound healing/Regeneration ▸ Wound healing

Standard StatusStandard

Sequence Length132 amino acids

Chemical FormulaC619H1003N173O174S21

DescriptionStandard

        MKSSGLFPFLVLLALGTLAPWAVEGSGKSFKAGVCPPKKSAQCLRYKKPECQSDWQCPGKKRCCPDTCGIKCLDPVDTPNPTRRKPGKCPVTYGQCLMLNPPNFCEMDGQCKRDLKCCMGMCGKSCVSPVKA
    

Molecular Weight14326.01 Da

Isoelectric Point (pI)9.11

Net Charge (pH 7.0)11.34

Net Charge (pH 7.4) 10.85

Charge Density (pH 7.0) 0.0859

GRAVY Index-0.31

Hydrophobic Moment 0.47

Boman Index-0.04

Instability Index40.40

Aliphatic Index 55.38

Aromaticity 0.0606

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5484.84

LogP -58.08

H-bond Donors 199.0

H-bond Acceptors 207.0

Rotatable Bonds 465.0

Heavy Atoms 987.0

Ring Count 25.0

Amide Bonds 139.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0270632 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antiparasitic Anti-tuberculosis Protease inhibitor Serine protease inhibitor Wound healing Enzyme Inhibitor Non-hemolytic

TargetNo Target Organism Found