Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC918H1417N255O270S9

DescriptionStandard

        MNLIKEFEGCRLTAYKPVPWEQMYTIGWGHYGVTAGTTWTQSQADSQLEIDINNKYAPMVDAYVKGKANQNEFDALVSLAYNCGNVFVADGWAEFSHAYCASMIPKYRNAGGQVLQGLVRRRQAELDLFNKPVTGSSNQNIQTKGEIKMYLIKGLDNSGKAKHWYISDGVSVRHIRTIRMLEN
    

Molecular Weight20634.20 Da

Isoelectric Point (pI)8.69

Net Charge (pH 7.0)2.83

Net Charge (pH 7.4) 2.32

Charge Density (pH 7.0) 0.0155

GRAVY Index-0.42

Hydrophobic Moment 0.63

Boman Index0.01

Instability Index36.15

Aliphatic Index 76.23

Aromaticity 0.1093

Extinction Coeff. Reduced 42400.00

Extinction Coeff. Oxidized 42525.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8528.52

LogP -93.87

H-bond Donors 296.0

H-bond Acceptors 286.0

Rotatable Bonds 685.0

Heavy Atoms 1452.0

Ring Count 34.0

Amide Bonds 205.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0121386 VERIFIED: NO

Provenance & Taxonomy

OrganismLactococcus phage PC_S1 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic