Peptide Database

Peptide NameHECATE 2DAc

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antiviral

Antiviral ▸ Anti-Retrovirus ▸ Anti-Lentivirus ▸ Anti-FIV

Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition ▸ Release inhibitor

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC123H226N32O24

DescriptionStandard

        FALALKALKKALKKLKKALKKAL
    

Molecular Weight2537.31 Da

Isoelectric Point (pI)10.90

Net Charge (pH 7.0)8.75

Net Charge (pH 7.4) 8.53

Charge Density (pH 7.0) 0.3805

GRAVY Index0.22

Hydrophobic Moment 0.80

Boman Index-0.05

Instability Index-12.58

Aliphatic Index 144.78

Aromaticity 0.0435

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 937.70

LogP -2.09

H-bond Donors 33.0

H-bond Acceptors 33.0

Rotatable Bonds 97.0

Heavy Atoms 179.0

Ring Count 1.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0424503 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyFLAK peptide

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Anticancer Cytotoxic

TargetHeLa

MethodMTT/MTS assay

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