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MYP_103073
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Basic Information
Recombinant Crassostrea Gigas Defensin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
43 amino acids
C190H303N61O59S8
Standard
Sequence
GFGCPGNQLKCNNHCKSISCRAGYCDAATLWLRCTCTDCNGKK
Physicochemical Analysis
4642.33 Da
8.73
3.77
3.39
0.0876
-0.41
0.44
-0.10
41.18
43.26
0.0698
6990.00
7490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1960.51
-27.13
76.0
72.0
152.0
318.0
6.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0284946 VERIFIED: YES
Provenance & Taxonomy
Crassostrea gigas [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
None
None
4-25, 11-34, 15-36, 20-39
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Salmonella typhimurium
20 μM
MIC
PMID16246846 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16246846/
RECORD: Rec_0312577 VERIFIED: YES
Provenance & Taxonomy
Magallana gigas [Animal]
Cg
29159
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperJ Biol Chem. 2006 Jan 6;281(1):313-23. | http://www.ncbi.nlm.nih.gov/pubmed/16246846 PMID16246846 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16246846/
RECORD: Rec_0315337 VERIFIED: YES
Provenance & Taxonomy
Crassostrea gigas [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
M. lysodeikticus
0.005-0.01 μM
MIC
PMID16246846 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16246846/
RECORD: Rec_0318118 VERIFIED: YES
Provenance & Taxonomy
Crassostrea gigas [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli 363
35-20 μM
MIC
PMID16246846 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16246846/
RECORD: Rec_0330430 VERIFIED: YES
Provenance & Taxonomy
Crassostrea gigas [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
None
None
4-25, 11-34, 15-36, 20-39
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Botrytis cinerea
20 μM
MIC
PMID16246846 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16246846/
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