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MYP_103073
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Basic Information
Recombinant Crassostrea Gigas Defensin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
43 amino acids
C190H303N61O59S8
Standard
Sequence
GFGCPGNQLKCNNHCKSISCRAGYCDAATLWLRCTCTDCNGKK
Physicochemical Analysis
4642.33 Da
8.73
3.77
3.39
0.0876
-0.41
0.44
-0.10
41.18
43.26
0.0698
6990.00
7490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1960.51
-27.13
76.0
72.0
152.0
318.0
6.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0060632 VERIFIED: YES
Provenance & Taxonomy
Crassostrea gigas [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
None
None
4-25, 11-34, 15-36, 20-39
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli 363
35-20 μM
MIC
PMID16246846 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16246846/
RECORD: Rec_0075792 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0076489 VERIFIED: YES
Provenance & Taxonomy
Crassostrea gigas [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
None
None
4-25, 11-34, 15-36, 20-39
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Fusarium oxysporum
9-4.5 μM
MIC
PMID16246846 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16246846/
RECORD: Rec_0103934 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 23.3%, E 14.0%, T 30.2%, C 32.6% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal Anti-Gram-positive
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0104832 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
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