Peptide Database

Peptide NameDefensin-TK

Function Ontology

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Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC188H286N50O56S7

DescriptionStandard

        SPALWGCDSFLGYCRIACFAHEASVGQKDCAEGMICCLPNV
    

Molecular Weight4367.04 Da

Isoelectric Point (pI)4.75

Net Charge (pH 7.0)-2.51

Net Charge (pH 7.4) -2.86

Charge Density (pH 7.0) -0.0611

GRAVY Index0.45

Hydrophobic Moment 0.42

Boman Index0.23

Instability Index51.71

Aliphatic Index 73.90

Aromaticity 0.0976

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1658.43

LogP -16.39

H-bond Donors 62.0

H-bond Acceptors 62.0

Rotatable Bonds 136.0

Heavy Atoms 301.0

Ring Count 8.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0217158 VERIFIED: YES

Provenance & Taxonomy

OrganismRhacophorus puerensis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)