Peptide Database

Peptide NameA36,42, 44 32-46Vu-Def

Function Ontology

Antimicrobial

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC72H120N28O22

DescriptionStandard

        LSGRARDDVRAWATR
    

Molecular Weight1729.90 Da

Isoelectric Point (pI)11.52

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.56

Charge Density (pH 7.0) 0.1175

GRAVY Index-0.96

Hydrophobic Moment 0.48

Boman Index-0.46

Instability Index-0.69

Aliphatic Index 65.33

Aromaticity 0.0667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 849.17

LogP -10.32

H-bond Donors 33.0

H-bond Acceptors 24.0

Rotatable Bonds 56.0

Heavy Atoms 122.0

Ring Count 2.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0025997 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiparasitic Antiprotozoal

TargetLeishmania amazonensis LV79

Activity74 μM

MethodMIC