Peptide Database

Peptide NameHymenochirin-1B

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC139H251N37O37S

DescriptionStandard

        IKLSPETKDNLKKVLKGAIKGAIAVAKMV
    

Molecular Weight3064.77 Da

Isoelectric Point (pI)10.13

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.54

Charge Density (pH 7.0) 0.1640

GRAVY Index0.17

Hydrophobic Moment 0.69

Boman Index0.06

Instability Index12.77

Aliphatic Index 124.48

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1209.62

LogP -8.69

H-bond Donors 41.0

H-bond Acceptors 43.0

Rotatable Bonds 111.0

Heavy Atoms 214.0

Ring Count 1.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0408362 VERIFIED: YES

Provenance & Taxonomy

OrganismHymenochirus boettgeri [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Hemolytic Anti-Gram-positive

TargetStaphylococcus aureus

Activity10 μM

MethodMIC

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