Peptide Database

Peptide NameLycotoxin-Pa4a (LCTX-Pa4a)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length122 amino acids

Chemical FormulaC605H971N169O184S15

DescriptionStandard

        MKLGIFFSVFFLAMIHSCLSETNEDKNLESYFREDDLKALSFGEYARAMMAESRKDNCIPKHHECTSRPKDCCKQNLMQFKCSCMTIIDKNNKETERCKCDNSIFQKVAKTSVNIGKAVVTK
    

Molecular Weight14037.18 Da

Isoelectric Point (pI)8.57

Net Charge (pH 7.0)3.69

Net Charge (pH 7.4) 3.14

Charge Density (pH 7.0) 0.0302

GRAVY Index-0.46

Hydrophobic Moment 0.57

Boman Index-0.12

Instability Index42.19

Aliphatic Index 62.38

Aromaticity 0.0820

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5787.61

LogP -60.98

H-bond Donors 208.0

H-bond Acceptors 206.0

Rotatable Bonds 489.0

Heavy Atoms 973.0

Ring Count 15.0

Amide Bonds 132.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0061445 VERIFIED: YES

Provenance & Taxonomy

OrganismPardosa astrigera [Animal]

FamilyNeurotoxin 19 (CSTX)

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Anti-inflammatory Non-hemolytic

TargetGram-negative and Gram-positive bacteria