Peptide Database

Peptide NameRegenerating islet-derived protein 3-beta (REG-3-beta) (Pancreatitis-associated protein 1) (Regenerating islet-derived protein III-beta) (Reg III-beta) [Cleaved into: Regenerating islet-derived protein 3-beta 16.5 kDa form; Regenerating islet-derived protein 3-beta 15 kDa form]

Function Ontology

Antimicrobial

Binding / Molecular interaction ▸ Carbohydrate-binding peptide ▸ Lectin

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length175 amino acids

Chemical FormulaC866H1314N230O253S15

DescriptionStandard

        MLPPTACSVMSWMLLSCLMLLSQVQGEDSLKNIPSARISCPKGSQAYGSYCYALFQIPQTWFDAELACQKRPGGHLVSVLNSAEASFLSSMVKRTGNSYQYTWIGLHDPTLGAEPNGGGWEWSNNDVMNYFNWERNPSTALDRAFCGSLSRASGFLKWRDMTCEVKLPYVCKFTG
    

Molecular Weight19476.06 Da

Isoelectric Point (pI)7.51

Net Charge (pH 7.0)0.61

Net Charge (pH 7.4) 0.14

Charge Density (pH 7.0) 0.0035

GRAVY Index-0.18

Hydrophobic Moment 0.64

Boman Index0.08

Instability Index39.96

Aliphatic Index 69.14

Aromaticity 0.1200

Extinction Coeff. Reduced 48930.00

Extinction Coeff. Oxidized 49430.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7704.54

LogP -79.50

H-bond Donors 275.0

H-bond Acceptors 271.0

Rotatable Bonds 622.0

Heavy Atoms 1364.0

Ring Count 40.0

Amide Bonds 190.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0078635 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Lectin Non-hemolytic

TargetS. enteritidis