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MYP_102977
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Basic Information
(FR)2-Protegrin 1 (8-13)-(RF)2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C93H141N35O15S2
Standard
Sequence
FRFRCRRRFCRFRF
Physicochemical Analysis
2053.47 Da
12.00
6.74
6.51
0.4814
-0.89
0.48
-0.80
91.11
0.00
0.3571
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
874.92
-6.38
38.0
24.0
67.0
145.0
5.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0138329 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacteriump yocyaneum
4 μM
MIC
PMID24621994 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24621994/
RECORD: Rec_0176990 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium
2 μM
MIC
PMID24621994 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24621994/
RECORD: Rec_0182571 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
1 μM
MIC
PMID24621994 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24621994/
RECORD: Rec_0194069 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis
2 μM
MIC
PMID24621994 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24621994/
RECORD: Rec_0202349 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
64 μM
Hemolysis
PMID24952979 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24952979/
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