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MYP_102956
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Basic Information
4W
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C90H131N29O14
Standard
Sequence
RWLRWWTRWRLK
Physicochemical Analysis
1843.19 Da
12.00
4.76
4.55
0.3966
-1.55
0.56
-0.53
159.10
65.00
0.3333
22000.00
22000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
740.43
-0.72
31.0
19.0
56.0
133.0
8.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0016056 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Salmonella typhi C77-31
PMID31276398 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31276398/
RECORD: Rec_0059188 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli 25922
PMID31276398 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31276398/
RECORD: Rec_0065405 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human red blood cells
128 μM
Hemolysis
PMID31276398 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31276398/
RECORD: Rec_0113173 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis 12228
4 μM
MIC
PaperDesign of Trp-Rich Dodecapeptides with Broad-Spectrum Antimicrobial Potency and Membrane-Disruptive Mechanism PMID31276398 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31276398/
RECORD: Rec_0147582 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus 25923
PMID31276398 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31276398/
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